Preclinical safety data also report natural S-Equol had little effect on 2 reproductive hormones
Natural S-equol, a novel soy germ-based compound, is very likely the primary ingredient for reducing hot flushes in the dietary supplement SE5-OH, which is under development for reduction of menopause symptoms, according to pre-clinical efficacy data from studies using an animal model presented at the Experimental Biology (EB) 2010 annual meeting. SE5-OH is in advanced studies in menopausal women, and peer-reviewed reports have previously documented that postmenopausal Japanese women receiving SE5-OH containing Natural S-equol significantly reduced the frequency of their hot flushes compared to women in the same study receiving a placebo (P=0.0092).
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